| Date | Opponent | Site | Time (ET) | Television | Score |
|---|
| 11/8 | McNEESE STATE COWBOYS | Breslin Center • East Lansing, Michigan | 7:00 PM |  | W 98-56 |
| Champions Classic |
| 11/12 | vs (1) Kentucky Wildcats | United Center • Chicago, Illinois | 7:30 PM |  | W 78-74 |
| Coaches vs. Cancer Classic |
| 11/15 | COLUMBIA LIONS | Breslin Center • East Lansing, Michigan | 9:00 PM |  | W 62-53 |
| 11/18 | PORTLAND PILOTS | Breslin Center • East Lansing, Michigan | 7:00 PM | | W 82-67 |
| 11/22 | vs Virginia Tech Hokies | Barclays Center • Brooklyn, New York | 9:30 PM |  | W 96-77 |
| 11/23 | vs Oklahoma Sooners | Barclays Center • Brooklyn, New York | 9:30 PM | | W 87-76 |
| 11/29 | MOUNT SAINT MARY'S MOUNTAINEERS | Breslin Center • East Lansing, Michigan | 1:00 PM |  | W 98-65 |
| Big Ten/ACC Challenge |
| 12/4 | (25) NORTH CAROLINA TAR HEELS | Breslin Center • East Lansing, Michigan | 9:00 PM | | L 79-65 |
| 12/14 | vs Oakland Golden Grizzlies | The Palace of Auburn Hills • Auburn Hills, Michigan | 4:00 PM |  | W 67-63 |
| 12/17 | NORTH FLORIDA OSPREYS | Breslin Center • East Lansing, Michigan | 7:00 PM | | W 78-48 |
| 12/21 | @ Texas Longhorns | Frank Erwin Center • Austin, Texas | 4:00 PM |  | W 92-78 |
| 12/28 | NEW ORLEANS PRIVATEERS | Breslin Center • East Lansing, Michigan | 4:15 PM | | W 101-48 |
| 12/31 | @ Penn State Nittany Lions | Bryce Jordan Center • University Park, Pennsylvania | 5:00 PM | | W 79-63 |
| 1/4 | @ Indiana Hoosiers | Assembly Hall • Bloomington, Indiana | 2:00 PM | | W 73-56 |
| 1/7 | (3) OHIO STATE BUCKEYES | Breslin Center • East Lansing, Michigan | 9:00 PM |  | W 72-68 (OT) |
| 1/11 | MINNESOTA GOLDEN GOPHERS | Breslin Center • East Lansing, Michigan | 2:15 PM | | W 87-75 (OT) |
| 1/15 | @ Northwestern Wildcats | Welsh-Ryan Arena • Evanston, Illinois | 7:00 PM | | W 54-40 |
| 1/18 | @ Illinois Fighting Illini | State Farm Center • Champaign, Illinois | 8:00 PM | | W 78-62 |
| 1/21 | INDIANA HOOSIERS | Breslin Center • East Lansing, Michigan | 7:00 PM | | W 71-66 |
| 1/25 | (21) MICHIGAN WOLVERINES | Breslin Center • East Lansing, Michigan | 7:00 PM | | L 80-75 |
| 1/28 | @ (12) Iowa Hawkeyes | Carver-Hawkeye Arena • Iowa City, Iowa | 7:00 PM | | W 71-69 (OT) |
| 2/1 | vs Georgetown Hoyas | Madison Square Garden • New York, New York | 3:00 PM |  | L 64-60 |
| 2/6 | PENN STATE NITTANY LIONS | Breslin Center • East Lansing, Michigan | 9:00 PM | | W 82-67 |
| 2/9 | @ (24) Wisconsin Badgers | Kohl Center • Madison, Wisconsin | 1:00 PM | | L 60-58 |
| 2/13 | NORTHWESTERN WILDCATS | Breslin Center • East Lansing, Michigan | 7:00 PM | | W 85-70 |
| 2/16 | NEBRASKA CORNHUSKERS | Breslin Center • East Lansing, Michigan | 3:00 PM | | L 60-51 |
| 2/20 | @ Purdue Boilermakers | Mackey Arena • West Lafayette, Indiana | 7:00 PM | | W 94-79 |
| 2/23 | @ (20) Michigan Wolverines | Crisler Arena • Ann Arbor, Michigan | 12:00 PM | | L 79-70 |
| 3/1 | ILLINOIS FIGHTING ILLINI | Breslin Center • East Lansing, Michigan | 4:00 PM | | L 53-46 |
| 3/6 | (24) IOWA HAWKEYES | Breslin Center • East Lansing, Michigan | 9:00 PM | | W 86-76 |
| 3/9 | @ Ohio State Buckeyes | Value City Arena • Columbus, Ohio | 4:30 PM | | L 69-67 |
| Big Ten Conference Tournament |
| 3/14 | vs (11) Northwestern Wildcats | Bankers Life Fieldhouse • Indianapolis, Indiana | 9:00 PM | | W 67-51 |
| 3/15 | vs (2) Wisconsin Badgers | Bankers Life Fieldhouse • Indianapolis, Indiana | 4:05 PM |  | W 83-75 |
| 3/16 | vs (1) Michigan Wolverines | Bankers Life Fieldhouse • Indianapolis, Indiana | 3:30 PM | | W 69-55 |
|
|---|
| NCAA Tournament - East Region |
| 3/20 | vs (13) Delaware Fightin' Blue Hens | Spokane Veterans Memorial Arena • Spokane, Washington | 4:40 PM |  | W 93-78 |
| 3/22 | vs (12) Harvard Crimson | Spokane Veterans Memorial Arena • Spokane, Washington | 8:40 PM | | W 80-73 |
| 3/28 | vs (1) Virginia Cavaliers | Madison Square Garden • New York, New York | 9:57 PM |  | W 61-59 |
| 3/30 | vs (7) Connecticut Huskies | Madison Square Garden • New York, New York | 2:20 PM | | L 60-54 |
| |
|---|
| BOLD = Michigan State Home Games |
|---|
| All Times are Eastern |
|---|
| (#) National Ranking of Opponent |
|---|
| (#) Tournament Seed of Opponent |
|---|
)