| Date | Opponent | Site | Time | Television | Score |
|---|
| 8/30 | FLORIDA ATLANTIC OWLS | Spartan Stadium • East Lansing, Michigan | 7:00 PM (EDT) | .png) | W 16-10 |
| 9/7 | @ Maryland Terrapins | SECU Stadium • College Park, Maryland | 3:30 PM (EDT) | | W 27-24 |
| 9/14 | PRAIRIE VIEW A&M PANTHERS | Spartan Stadium • East Lansing, Michigan | 3:30 PM (EDT) | | W 40-0 |
| 9/21 | @ Boston College Eagles | Alumni Stadium • Chestnut Hill, Massachusetts | 8:00 PM (EDT) | .png) | L 23-19 |
| 9/28 | (3) OHIO STATE BUCKEYES | Spartan Stadium • East Lansing, Michigan | 7:30 PM (EDT) | .png) | L 38-7 |
| 10/4 | @ (6) Oregon Ducks | Autzen Stadium • Eugune, Oregon | 9:00 PM (EDT) | .png) | L 31-10 |
| 10/19 | IOWA HAWKEYES | Spartan Stadium • East Lansing, Michigan | 7:30 PM (EDT) | .png) | W 32-20 |
| 10/26 | @ Michigan Wolverines | Michigan Stadium • Ann Arbor, Michigan | 7:30 PM (EDT) | | L 24-17 |
| 11/2 | (13) INDIANA HOOSIERS | Spartan Stadium • East Lansing, Michigan | 3:30 PM (EDT) | | L 47-10 |
| 11/16 | @ Illinois Fighting Illini | Memorial Stadium • Champaign, Illinois | 2:30 PM (EST) | .png) | L 38-16 |
| 11/22 | PURDUE BOILERMAKERS | Spartan Stadium • East Lansing, Michigan | 8:00 PM (EST) | | W 24-17 |
| 11/30 | RUTGERS SCARLET KNIGHTS | Spartan Stadium • East Lansing, Michigan | 3:30 PM (EST) | | - |
| |
|---|
| BOLD = Michigan State Home Games |
|---|
